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Human Immunodeficiency Virus Type 1 Replication in the Absence of Integrase-Mediated DNA Recombination: Definition of Permissive and Nonpermissive T-Cell Lines

Functional retroviral integrase protein is thought to be essential for productive viral replication. Yet, previous studies differed on the extent to which integrase mutant viruses expressed human immunodeficiency virus type 1 (HIV-1) genes from unintegrated DNA. Although one reason for this differen...

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Bibliographic Details
Main Authors: Nakajima, Noriko, Lu, Richard, Engelman, Alan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC115038/
https://ncbi.nlm.nih.gov/pubmed/11483739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.7944-7955.2001
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