Structure-Based Mutagenesis of the Human Immunodeficiency Virus Type 1 DNA Attachment Site: Effects on Integration and cDNA Synthesis

Sequences at the ends of linear retroviral cDNA important for integration define the viral DNA attachment (att) site. Whereas determinants of human immunodeficiency virus type 1 (HIV-1) integrase important for replication in T lymphocytes have been extensively characterized, regions of the att site...

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Hlavní autoři: Brown, Heidi E. V., Chen, Hongmin, Engelman, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC112933/
https://ncbi.nlm.nih.gov/pubmed/10516007
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