Trimethoprim resistance in Haemophilus influenzae is due to altered dihydrofolate reductase(s).

We characterized a highly purified preparation of the chromosomally encoded dihydrofolate reductase (DHFR) from a trimethoprim-susceptible (Tmp8; strain MAP) and two trimethoprim-resistant (TmpR) strains (MAP/47 and MAP/42) of Haemophilus influenzae. The enzymes were purified between 650- and 3000-f...

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Bibliografski detalji
Glavni autori: de Groot, R, Chaffin, D O, Kuehn, M, Smith, A L
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149962/
https://ncbi.nlm.nih.gov/pubmed/2012595
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