Genetic characterization of trimethoprim resistance in Haemophilus influenzae.

We previously demonstrated that trimethoprim (Tmp) resistance in Haemophilus influenzae is mediated by chromosomally encoded dihydrofolate reductase (DHFR) with a modified primary structure and distinct kinetic properties. To gain insight into the relationship of the DHFR structure and the level of...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	de Groot, R, Sluijter, M, de Bruyn, A, Campos, J, Goessens, W H, Smith, A L, Hermans, P W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.9.2131
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