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Genetic characterization of trimethoprim resistance in Haemophilus influenzae.

We previously demonstrated that trimethoprim (Tmp) resistance in Haemophilus influenzae is mediated by chromosomally encoded dihydrofolate reductase (DHFR) with a modified primary structure and distinct kinetic properties. To gain insight into the relationship of the DHFR structure and the level of...

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Bibliografische gegevens
Hoofdauteurs: de Groot, R, Sluijter, M, de Bruyn, A, Campos, J, Goessens, W H, Smith, A L, Hermans, P W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC163486/
https://ncbi.nlm.nih.gov/pubmed/8878594
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