Recombinant Measles Viruses Expressing Altered Hemagglutinin (H) Genes: Functional Separation of Mutations Determining H Antibody Escape from Neurovirulence

Measles virus (MV) strain CAM/RB, which was adapted to growth in the brain of newborn rodents, is highly neurovirulent. It has been reported earlier that experimentally selected virus variants escaping from the monoclonal antibodies (MAbs) Nc32 and L77 to hemagglutinin (H) preserved their neurovirul...

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Detalhes bibliográficos
Main Authors: Moeller, Kerstin, Duffy, Iain, Duprex, Paul, Rima, Bert, Beschorner, Rudi, Fauser, Susanne, Meyermann, Richard, Niewiesk, Stefan, ter Meulen, Volker, Schneider-Schaulies, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114996/
https://ncbi.nlm.nih.gov/pubmed/11462033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7612-7620.2001
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