Amino Acid Deletion at Codon 67 and Thr-to-Gly Change at Codon 69 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Novel Drug Resistance Profiles

The potential roles of an amino acid deletion at codon 67 (Δ67) and a Thr-to-Gly change at codon 69 (T69G) in the reverse transcriptase of human immunodeficiency virus (HIV) type 1 in drug sensitivity and relative replication fitness were studied. Our results suggest that the Δ67 and T69G changes ca...

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Detalhes bibliográficos
Main Authors: Imamichi, Tomozumi, Murphy, Michael A., Imamichi, Hiromi, Lane, H. Clifford
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114891/
https://ncbi.nlm.nih.gov/pubmed/11264389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.3988-3992.2001
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