Amino Acid Deletion at Codon 67 and Thr-to-Gly Change at Codon 69 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Novel Drug Resistance Profiles

The potential roles of an amino acid deletion at codon 67 (Δ67) and a Thr-to-Gly change at codon 69 (T69G) in the reverse transcriptase of human immunodeficiency virus (HIV) type 1 in drug sensitivity and relative replication fitness were studied. Our results suggest that the Δ67 and T69G changes ca...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Imamichi, Tomozumi, Murphy, Michael A., Imamichi, Hiromi, Lane, H. Clifford
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114891/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11264389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.8.3988-3992.2001
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