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Glucocorticoids increase insulin binding and the amount of insulin-receptor mRNA in human cultured lymphocytes.

The effect of steroid hormones on insulin binding and the amount of insulin-receptor mRNA was examined in IM-9 lymphocytes. Cortisol and cortexolone, but not oestrogen, increased both the binding of insulin and the amount of insulin-receptor mRNA in a time- and dose-dependent manner. Cortisol was mo...

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Bibliografiske detaljer
Main Authors: Shibasaki, Y, Sakura, H, Odawara, M, Shibuya, M, Kanazawa, Y, Akanuma, Y, Takaku, F, Kasuga, M
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148765/
https://ncbi.nlm.nih.gov/pubmed/3281654
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