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Region of Herpes Simplex Virus Type 1 Latency-Associated Transcript Sufficient for Wild-Type Spontaneous Reactivation Promotes Cell Survival in Tissue Culture

The latency-associated transcript (LAT) is the only abundant herpes simplex virus type 1 (HSV-1) transcript expressed during latency. In the rabbit eye model, LAT null mutants do not reactivate efficiently from latency. We recently demonstrated that the LAT null mutant dLAT2903 induces increased lev...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Inman, Melissa, Perng, Guey-Chuen, Henderson, Gail, Ghiasi, Homayon, Nesburn, Anthony B., Wechsler, Steven L., Jones, Clinton
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114855/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11264353/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.8.3636-3646.2001
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