Region of Herpes Simplex Virus Type 1 Latency-Associated Transcript Sufficient for Wild-Type Spontaneous Reactivation Promotes Cell Survival in Tissue Culture

The latency-associated transcript (LAT) is the only abundant herpes simplex virus type 1 (HSV-1) transcript expressed during latency. In the rabbit eye model, LAT null mutants do not reactivate efficiently from latency. We recently demonstrated that the LAT null mutant dLAT2903 induces increased lev...

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Detalhes bibliográficos
Main Authors: Inman, Melissa, Perng, Guey-Chuen, Henderson, Gail, Ghiasi, Homayon, Nesburn, Anthony B., Wechsler, Steven L., Jones, Clinton
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114855/
https://ncbi.nlm.nih.gov/pubmed/11264353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.3636-3646.2001
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