Antigenicity and Immunogenicity of Novel Chimeric Hepatitis B Surface Antigen Particles with Exposed Hepatitis C Virus Epitopes

The small envelope protein of hepatitis B virus (HBsAg-S) can self-assemble into highly organized virus like particles (VLPs) and induce an effective immune response. In this study, a restriction enzyme site was engineered into the cDNA of HBsAg-S at a position corresponding to the exposed site with...

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Bibliographic Details
Main Authors: Netter, Hans J., Macnaughton, Thomas B., Woo, Wai-Ping, Tindle, Robert, Gowans, Eric J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114797/
https://ncbi.nlm.nih.gov/pubmed/11160717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.5.2130-2141.2001
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