Antigenicity and Immunogenicity of Novel Chimeric Hepatitis B Surface Antigen Particles with Exposed Hepatitis C Virus Epitopes

The small envelope protein of hepatitis B virus (HBsAg-S) can self-assemble into highly organized virus like particles (VLPs) and induce an effective immune response. In this study, a restriction enzyme site was engineered into the cDNA of HBsAg-S at a position corresponding to the exposed site with...

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Pubblicato in:	J Virol
Autori principali:	Netter, Hans J., Macnaughton, Thomas B., Woo, Wai-Ping, Tindle, Robert, Gowans, Eric J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Vaccines and Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114797/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160717/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.5.2130-2141.2001
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