Unique Monoclonal Antibody Recognizing the Third Extracellular Loop of CXCR4 Induces Lymphocyte Agglutination and Enhances Human Immunodeficiency Virus Type 1-Mediated Syncytium Formation and Productive Infection

To increase insight into the structural basis of CXCR4 utilization in human immunodeficiency virus type 1 (HIV-1) infection, a new generation of three monoclonal antibodies (MAbs) was developed in WKA rats. The A80 MAb, which binds an epitope in the third extracellular loop (ECL3) of CXCR4, has uniq...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	J Virol
المؤلفون الرئيسيون:	Tanaka, Reiko, Yoshida, Atsushi, Murakami, Tsutomu, Baba, Eishi, Lichtenfeld, Julliane, Omori, Takeru, Kimura, Tohru, Tsurutani, Naomi, Fujii, Nobutaka, Wang, Zi-Xuan, Peiper, Stephen C., Yamamoto, Naoki, Tanaka, Yuetsu
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	American Society for Microbiology (ASM) 2001
الموضوعات:	Pathogenesis and Immunity
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.23.11534-11543.2001
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