A thiol-sensitive degradative process of liver uncouples autophosphorylation of the insulin receptor from insulin binding.

Insulin receptors derived from highly purified rat liver plasma membranes and Golgi membranes showed differences in insulin-mediated receptor autophosphorylation, even though their insulin-binding characteristics were similar. This difference was related to the generation of a Mr-84,000 fragment of...

Full description

Saved in:
Bibliographic Details
Main Authors: Lerea, K M, Livingston, J N
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1146873/
https://ncbi.nlm.nih.gov/pubmed/3092812
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items