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Differential sensitivity of the insulin-receptor kinase to thiol and oxidizing agents in the absence and presence of insulin.

The purified human placental insulin-receptor beta-subunit autophosphorylating activity was found to be inhibited, in a time- and concentration-dependent manner, by the specific thiol-alkylating agents N-ethylmaleimide and 5,5'-dithiobis-(2-nitrobenzoic acid). The insulin-receptor kinase was ob...

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Main Authors: Wilden, P A, Pessin, J E
格式: Artigo
語言:Inglês
出版: 1987
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148125/
https://ncbi.nlm.nih.gov/pubmed/2822020
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