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Purification and characterization of dihydrofolate reductase from Mycobacterium phlei.

The dihydrofolate reductase from Mycobacterium phlei was purified and characterized; it has an Mr of 15 000 and a pI of 4.8. It is competitively inhibited by both methotrexate and trimethoprim, although the affinity is less than for other bacterial dihydrofolate reductases.

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Al-Rubeai, M, Dale, J W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1986
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1146682/
https://ncbi.nlm.nih.gov/pubmed/3741386
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