A Novel CD8-Independent High-Avidity Cytotoxic T-Lymphocyte Response Directed against an Epitope in the Phosphoprotein of the Paramyxovirus Simian Virus 5

Adoptive transfer studies have shown that cytotoxic T lymphocytes (CTL) of high avidity, capable of recognizing low levels of peptide-MHC I molecules, are more efficient at reducing viral titers than are low-avidity CTL, thus establishing CTL avidity as a critical parameter for the ability of a CTL...

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Detalhes bibliográficos
Main Authors: Gray, Peter M., Parks, Griffith D., Alexander-Miller, Martha A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114581/
https://ncbi.nlm.nih.gov/pubmed/11581375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10065-10072.2001
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