Novel cis-Acting Replication Element in the Adeno-Associated Virus Type 2 Genome Is Involved in Amplification of Integrated rep-cap Sequences

This study identifies a region of the adeno-associated virus type 2 (AAV-2) rep gene (nucleotides 190 to 540 of wild-type AAV-2) as a cis-acting Rep-dependent element able to promote the replication of transiently transfected plasmids. This viral element is also shown to be involved in the amplifica...

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Detalhes bibliográficos
Main Authors: Nony, Pascale, Tessier, Jacques, Chadeuf, Gilliane, Ward, Peter, Giraud, Aurélie, Dugast, Marc, Linden, R. Michael, Moullier, Philippe, Salvetti, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114572/
https://ncbi.nlm.nih.gov/pubmed/11559833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9991-9994.2001
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