Novel cis-Acting Replication Element in the Adeno-Associated Virus Type 2 Genome Is Involved in Amplification of Integrated rep-cap Sequences

This study identifies a region of the adeno-associated virus type 2 (AAV-2) rep gene (nucleotides 190 to 540 of wild-type AAV-2) as a cis-acting Rep-dependent element able to promote the replication of transiently transfected plasmids. This viral element is also shown to be involved in the amplifica...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Nony, Pascale, Tessier, Jacques, Chadeuf, Gilliane, Ward, Peter, Giraud, Aurélie, Dugast, Marc, Linden, R. Michael, Moullier, Philippe, Salvetti, Anna
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114572/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11559833/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.20.9991-9994.2001
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