Conserved CDR3 Regions in T-Cell Receptor (TCR) CD8(+) T Cells That Recognize the Tax11-19/HLA-A*0201 Complex in a Subject Infected with Human T-Cell Leukemia Virus Type 1: Relationship of T-Cell Fine Specificity and Major Histocompatibility Complex/Peptide/TCR Crystal Structure

We investigated the T-cell receptor (TCR) repertoire of CD8(+) T cells that recognize the Tax11-19 immunodominant epitope of Tax protein expressed by human T-cell leukemia virus (HTLV-1) that is implicated in the disease HTLV-1-associated myelopathy (HAM/TSP). A panel of Tax11-19-reactive CD8(+) T-c...

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Detalhes bibliográficos
Main Authors: Bourcier, Katarzyna D., Lim, Dong-Gyun, Ding, Yuan-Hua, Smith, Kathrine J., Wucherpfennig, Kai, Hafler, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114556/
https://ncbi.nlm.nih.gov/pubmed/11559817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9836-9843.2001
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