Binding of TCR Multimers and a TCR-Like Antibody with Distinct Fine-Specificities Is Dependent on the Surface Density of HLA Complexes

Class I Major Histocompatibility Complex (MHC) molecules evolved to sample degraded protein fragments from the interior of the cell, and to display them at the surface for immune surveillance by CD8(+) T cells. The ability of these lymphocytes to identify immunogenic peptide-MHC (pMHC) products on,...

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Detalhes bibliográficos
Main Authors: Low, Jianrong L., Naidoo, Anneta, Yeo, Gladys, Gehring, Adam J., Ho, Zi Zong, Yau, Yin Hoe, Shochat, Susana G., Kranz, David M., Bertoletti, Antonio, Grotenbreg, Gijsbert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519586/
https://ncbi.nlm.nih.gov/pubmed/23251518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051397
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