Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects.
The major histocompatibility complex (MHC) region is strongly associated with multiple sclerosis (MS) susceptibility. HLA-DRB1*15:01 has the strongest effect, and several other alleles have been reported at different levels of validation. Using SNP data from genome-wide studies, we imputed and teste...
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| المؤلفون الرئيسيون: | , , , , , , , , , , , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science (PLoS)
2013-11-01
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| سلاسل: | PLoS Genetics |
| الوصول للمادة أونلاين: | https://doi.org/10.1371/journal.pgen.1003926 |
| الوسوم: |
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