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Mutation of the Methylated tRNA [Formula: see text] Residue A58 Disrupts Reverse Transcription and Inhibits Replication of Human Immunodeficiency Virus Type 1
Cellular tRNA [Formula: see text] serves as the primer for reverse transcription of human immunodeficiency virus type 1 (HIV-1). tRNA [Formula: see text] interacts directly with HIV-1 reverse transcriptase (RT), is packaged into viral particles, and anneals to the primer-binding site (PBS) of the HI...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2001
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114538/ https://ncbi.nlm.nih.gov/pubmed/11559799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9671-9678.2001 |
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