Effect on DNA relaxation of the single Thr718Ala mutation in human topoisomerase I: a functional and molecular dynamics study

Lignende værker

• Protein concerted motions in the DNA–human topoisomerase I complex
  af: Chillemi, Giovanni, et al.
  Udgivet: (2003)
• Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations
  af: Chillemi, Giovanni, et al.
  Udgivet: (2008)
• The open state of human topoisomerase I as probed by molecular dynamics simulation
  af: Chillemi, Giovanni, et al.
  Udgivet: (2007)
• The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant
  af: Fiorani, Paola, et al.
  Udgivet: (2006)
• A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance
  af: Losasso, Carmen, et al.
  Udgivet: (2008)