Differences between collagen hydroxylases and 2-oxoglutarate dehydrogenase in their inhibition by structural analogues of 2-oxoglutarate.

Inhibition of lysyl hydroxylase and prolyl 3-hydroxylase was studied with 23 selected aromatic and aliphatic structural analogues of 2-oxoglutarate and the results were compared with those previously reported for prolyl 4-hydroxylase. All the compounds inhibited the hydroxylases competitively with r...

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Detalhes bibliográficos
Main Authors: Majamaa, K, Turpeenniemi-Hujanen, T M, Latipää, P, Günzler, V, Hanauske-Abel, H M, Hassinen, I E, Kivirikko, K I
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1145158/
https://ncbi.nlm.nih.gov/pubmed/2994628
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