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Correlation between Viral Resistance to Zidovudine and Resistance at the Reverse Transcriptase Level for a Panel of Human Immunodeficiency Virus Type 1 Mutants

Using a large panel of human immunodeficiency virus type 1 site-directed mutants, we have observed a higher correlation than has previously been demonstrated between zidovudine (AZT)-triphosphate resistance data at the reverse transcriptase (RT) level and corresponding viral AZT resistance. This enh...

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Udgivet i:J Virol
Principais autores: Lennerstrand, Johan, Hertogs, Kurt, Stammers, David K., Larder, Brendan A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114451/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11435603/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.15.7202-7205.2001
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