Correlation between Viral Resistance to Zidovudine and Resistance at the Reverse Transcriptase Level for a Panel of Human Immunodeficiency Virus Type 1 Mutants

Using a large panel of human immunodeficiency virus type 1 site-directed mutants, we have observed a higher correlation than has previously been demonstrated between zidovudine (AZT)-triphosphate resistance data at the reverse transcriptase (RT) level and corresponding viral AZT resistance. This enh...

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Detalles Bibliográficos
Main Authors: Lennerstrand, Johan, Hertogs, Kurt, Stammers, David K., Larder, Brendan A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC114451/
https://ncbi.nlm.nih.gov/pubmed/11435603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.15.7202-7205.2001
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