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Thrombospondin fragmentation by alpha-thrombin and resistance to gamma-thrombin.

In the presence of 2mM-Ca2+, alpha-thrombin slowly cleaved thrombospondin (Mr 180 000) into 150 000-Mr and 30 000-Mr fragments. In the absence of Ca2+, the platelet glycoprotein was progressively and completely hydrolysed by 3 units of the enzyme/ml to 130 000-Mr, 95 000-Mr and 65 000-Mr fragments....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Takahashi, K, Aiken, M, Fenton, J W, Walz, D A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1984
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144480/
https://ncbi.nlm.nih.gov/pubmed/6517871
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