The mechanism of pyrophosphorolysis of RNA by RNA polymerase. Endowment of RNA polymerase with artificial exonuclease activity.

DNA-directed RNA polymerase from Escherichia coli can break down RNA by catalysing the reverse of the reaction: NTP + (RNA)n = (RNA)n+1 + PPi where n indicates the number of nucleotide residues in the RNA molecule, to yield nucleoside triphosphates. This reaction requires the ternary complex of the...

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Detalhes bibliográficos
Main Authors: Rozovskaya, T A, Rechinsky, V O, Bibilashvili, R S, Karpeisky MYa, Tarusova, N B, Khomutov, R M, Dixon, H B
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144476/
https://ncbi.nlm.nih.gov/pubmed/6083781
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