A Predicted Secondary Structural Domain within the Internal Ribosome Entry Site of Echovirus 12 Mediates a Cell-Type-Specific Block to Viral Replication

The enterovirus 5′ nontranslated region (NTR) contains an internal ribosome entry site (IRES), which facilitates translation initiation of the viral open reading frame in a 5′ (m(7)GpppN) cap-independent manner, and cis-acting signals for positive-strand RNA replication. For several enteroviruses, t...

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Bibliographic Details
Main Authors: Bradrick, Shelton S., Lieben, Elizabeth A., Carden, Bruce M., Romero, José R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114370/
https://ncbi.nlm.nih.gov/pubmed/11413314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.14.6472-6481.2001
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