Cytokine Production by Vγ(+)-T-Cell Subsets Is an Important Factor Determining CD4(+)-Th-Cell Phenotype and Susceptibility of BALB/c Mice to Coxsackievirus B3-Induced Myocarditis

Two coxsackievirus B3 (CVB3) variants (H3 and H310A1) differ by a single amino acid mutation in the VP2 capsid protein. H3 induces severe myocarditis in BALB/c mice, but H310A1 is amyocarditic. Infection with H3, but not H310A1, preferentially activates Vγ4 Vδ4 cells, which are strongly positive for...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Huber, Sally A., Graveline, Danielle, Born, Willi K., O'Brien, Rebecca L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.5860-5869.2001
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