Conservation of the Conformation and Positive Charges of Hepatitis C Virus E2 Envelope Glycoprotein Hypervariable Region 1 Points to a Role in Cell Attachment

Chronic hepatitis C virus (HCV) infection is a major cause of liver disease. The HCV polyprotein contains a hypervariable region (HVR1) located at the N terminus of the second envelope glycoprotein E2. The strong variability of this 27-amino-acid region is due to its apparent tolerance of amino acid...

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Detalhes bibliográficos
Main Authors: Penin, François, Combet, Christophe, Germanidis, Georgios, Frainais, Pierre-Olivier, Deléage, Gilbert, Pawlotsky, Jean-Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114285/
https://ncbi.nlm.nih.gov/pubmed/11356980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.12.5703-5710.2001
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