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Conservation of the Conformation and Positive Charges of Hepatitis C Virus E2 Envelope Glycoprotein Hypervariable Region 1 Points to a Role in Cell Attachment

Chronic hepatitis C virus (HCV) infection is a major cause of liver disease. The HCV polyprotein contains a hypervariable region (HVR1) located at the N terminus of the second envelope glycoprotein E2. The strong variability of this 27-amino-acid region is due to its apparent tolerance of amino acid...

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Udgivet i:J Virol
Principais autores: Penin, François, Combet, Christophe, Germanidis, Georgios, Frainais, Pierre-Olivier, Deléage, Gilbert, Pawlotsky, Jean-Michel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114285/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11356980/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.12.5703-5710.2001
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