Mapping the Determinants of the CCR5 Amino-Terminal Sulfopeptide Interaction with Soluble Human Immunodeficiency Virus Type 1 gp120-CD4 Complexes

CD4 and CCR5 mediate fusion and entry of R5 human immunodeficiency virus type 1 (HIV-1) strains. Sulfotyrosine and other negatively charged residues in the CCR5 amino-terminal domain (Nt) are crucial for gp120 binding and viral entry. We previously showed that a soluble gp120-CD4 complex specificall...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Cormier, Emmanuel G., Tran, Diep N. H., Yukhayeva, Liyana, Olson, William C., Dragic, Tatjana
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114266/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11356961/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.12.5541-5549.2001
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