Sec17p and HOPS, in distinct SNARE complexes, mediate SNARE complex disruption or assembly for fusion

SNARE functions during membrane docking and fusion are regulated by Sec1/Munc18 (SM) chaperones and Rab/Ypt GTPase effectors. These functions for yeast vacuole fusion are combined in the six-subunit HOPS complex. HOPS facilitates Ypt7p nucleotide exchange, is a Ypt7p effector, and contains an SM pro...

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Bibliographic Details
Main Authors: Collins, Kevin M, Thorngren, Naomi L, Fratti, Rutilio A, Wickner, William T
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142591/
https://ncbi.nlm.nih.gov/pubmed/15889152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600658
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