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Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p

Coupling of Rab GTPase activation and SNARE complex assembly during membrane fusion is poorly understood. The homotypic fusion and vacuole protein sorting (HOPS) complex links these two processes: it is an effector for the vacuolar Rab GTPase Ypt7p and is required for vacuolar SNARE complex assembly...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stroupe, Christopher, Collins, Kevin M, Fratti, Rutilio A, Wickner, William
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440844/
https://ncbi.nlm.nih.gov/pubmed/16601699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601051
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