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Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p

Coupling of Rab GTPase activation and SNARE complex assembly during membrane fusion is poorly understood. The homotypic fusion and vacuole protein sorting (HOPS) complex links these two processes: it is an effector for the vacuolar Rab GTPase Ypt7p and is required for vacuolar SNARE complex assembly...

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Hlavní autoři: Stroupe, Christopher, Collins, Kevin M, Fratti, Rutilio A, Wickner, William
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440844/
https://ncbi.nlm.nih.gov/pubmed/16601699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601051
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