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Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis
The inactivation of glycogen synthase kinase (GSK)3 has been proposed to play important roles in insulin and Wnt signalling. To define the role that inactivation of GSK3 plays, we generated homozygous knockin mice in which the protein kinase B phosphorylation sites on GSK3α (Ser21) and GSK3β (Ser9)...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142569/ https://ncbi.nlm.nih.gov/pubmed/15791206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600633 |
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