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Direct molecular haplotyping by melting curve analysis of hybridization probes: beta 2-adrenergic receptor haplotypes as an example

Direct determination of the association of multiple genetic polymorphisms, or haplotyping, in individual samples is challenging because of chromosome diploidy. Here, we describe the ability of hybridization probes, commonly used as genotyping tools, to establish single nucleotide polymorphism (SNP)...

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Detalhes bibliográficos
Main Authors: Pont-Kingdon, Genevieve, Lyon, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142492/
https://ncbi.nlm.nih.gov/pubmed/15937194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni090
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