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Direct molecular haplotyping by melting curve analysis of hybridization probes: beta 2-adrenergic receptor haplotypes as an example

Direct determination of the association of multiple genetic polymorphisms, or haplotyping, in individual samples is challenging because of chromosome diploidy. Here, we describe the ability of hybridization probes, commonly used as genotyping tools, to establish single nucleotide polymorphism (SNP)...

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Bibliografische gegevens
Hoofdauteurs: Pont-Kingdon, Genevieve, Lyon, Elaine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142492/
https://ncbi.nlm.nih.gov/pubmed/15937194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni090
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