Identification of a Novel Posttranscriptional Regulatory Element by Using a rev- and RRE-Mutated Human Immunodeficiency Virus Type 1 DNA Proviral Clone as a Molecular Trap

Human immunodeficiency virus (HIV) and all other lentiviruses utilize the essential viral protein Rev, which binds to RRE RNA, to export their unspliced and partially spliced mRNAs from the nucleus. We used a rev- and RRE-defective HIV type 1 (HIV-1) molecular clone in complementation experiments to...

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Detalhes bibliográficos
Main Authors: Nappi, Filomena, Schneider, Ralf, Zolotukhin, Andrei, Smulevitch, Sergey, Michalowski, Daniel, Bear, Jenifer, Felber, Barbara K., Pavlakis, George N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114209/
https://ncbi.nlm.nih.gov/pubmed/11312326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.10.4558-4569.2001
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