Identification of a Novel Posttranscriptional Regulatory Element by Using a rev- and RRE-Mutated Human Immunodeficiency Virus Type 1 DNA Proviral Clone as a Molecular Trap

Human immunodeficiency virus (HIV) and all other lentiviruses utilize the essential viral protein Rev, which binds to RRE RNA, to export their unspliced and partially spliced mRNAs from the nucleus. We used a rev- and RRE-defective HIV type 1 (HIV-1) molecular clone in complementation experiments to...

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Main Authors: Nappi, Filomena, Schneider, Ralf, Zolotukhin, Andrei, Smulevitch, Sergey, Michalowski, Daniel, Bear, Jenifer, Felber, Barbara K., Pavlakis, George N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC114209/
https://ncbi.nlm.nih.gov/pubmed/11312326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.10.4558-4569.2001
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