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Identification of a Novel Posttranscriptional Regulatory Element by Using a rev- and RRE-Mutated Human Immunodeficiency Virus Type 1 DNA Proviral Clone as a Molecular Trap

Human immunodeficiency virus (HIV) and all other lentiviruses utilize the essential viral protein Rev, which binds to RRE RNA, to export their unspliced and partially spliced mRNAs from the nucleus. We used a rev- and RRE-defective HIV type 1 (HIV-1) molecular clone in complementation experiments to...

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Udgivet i:J Virol
Principais autores: Nappi, Filomena, Schneider, Ralf, Zolotukhin, Andrei, Smulevitch, Sergey, Michalowski, Daniel, Bear, Jenifer, Felber, Barbara K., Pavlakis, George N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114209/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11312326/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.10.4558-4569.2001
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