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Multiple Immediate-Early Gene-Deficient Herpes Simplex Virus Vectors Allowing Efficient Gene Delivery to Neurons in Culture and Widespread Gene Delivery to the Central Nervous System In Vivo

Herpes simplex virus (HSV) has several potential advantages as a vector for delivering genes to the nervous system. The virus naturally infects and remains latent in neurons and has evolved the ability of highly efficient retrograde transport from the site of infection at the periphery to the site o...

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Bibliografiske detaljer
Main Authors: Lilley, Caroline E., Groutsi, Filitsa, Han, ZiQun, Palmer, James A., Anderson, Patrick N., Latchman, David S., Coffin, Robert S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114179/
https://ncbi.nlm.nih.gov/pubmed/11287583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.9.4343-4356.2001
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