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Development and Optimization of Herpes Simplex Virus Vectors for Multiple Long-Term Gene Delivery to the Peripheral Nervous System

Herpes simplex virus (HSV) has often been suggested as a suitable vector for gene delivery to the peripheral nervous system as it naturally infects sensory nerve terminals before retrograde transport to the cell body in the spinal ganglia where latency is established. HSV vectors might therefore be...

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Detalhes bibliográficos
Main Authors: Palmer, J. A., Branston, R. H., Lilley, C. E., Robinson, M. J., Groutsi, F., Smith, J., Latchman, D. S., Coffin, R. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112048/
https://ncbi.nlm.nih.gov/pubmed/10823868
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