Equine Herpesvirus 1 Gene 12 Can Substitute for vmw65 in the Growth of Herpes Simplex Virus (HSV) Type 1, Allowing the Generation of Optimized Cell Lines for the Propagation of HSV Vectors with Multiple Immediate-Early Gene Defects

Herpes simplex virus (HSV) has often been suggested for development as a vector, particularly for the nervous system. Considerable evidence has shown that for use of HSV as a vector, immediate-early (IE) gene expression must be minimized or abolished, otherwise such vectors are likely to be highly c...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Thomas, S. K., Lilley, C. E., Latchman, D. S., Coffin, R. S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104267/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438830/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7399-7409.1999
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