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Equine Herpesvirus 1 Gene 12 Can Substitute for vmw65 in the Growth of Herpes Simplex Virus (HSV) Type 1, Allowing the Generation of Optimized Cell Lines for the Propagation of HSV Vectors with Multiple Immediate-Early Gene Defects

Herpes simplex virus (HSV) has often been suggested for development as a vector, particularly for the nervous system. Considerable evidence has shown that for use of HSV as a vector, immediate-early (IE) gene expression must be minimized or abolished, otherwise such vectors are likely to be highly c...

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Udgivet i:J Virol
Principais autores: Thomas, S. K., Lilley, C. E., Latchman, D. S., Coffin, R. S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104267/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7399-7409.1999
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