The C-terminal 79 amino acids of the herpes simplex virus regulatory protein, Vmw65, efficiently activate transcription in yeast and mammalian cells in chimeric DNA-binding proteins.

Activation of herpes simplex virus immediate early gene expression normally requires the formation of a ternary complex between a virus trans-activator, Vmw65, a cellular octamer-binding protein, TRF and the cis-acting target sequence, the TAATGARAT motif. We report that the C-terminal 79 amino acid...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Cousens, D J, Greaves, R, Goding, C R, O'Hare, P
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2676518/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08361.x
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