The C-terminal 79 amino acids of the herpes simplex virus regulatory protein, Vmw65, efficiently activate transcription in yeast and mammalian cells in chimeric DNA-binding proteins.

Activation of herpes simplex virus immediate early gene expression normally requires the formation of a ternary complex between a virus trans-activator, Vmw65, a cellular octamer-binding protein, TRF and the cis-acting target sequence, the TAATGARAT motif. We report that the C-terminal 79 amino acid...

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Publicado en:	EMBO J
Autores principales:	Cousens, D J, Greaves, R, Goding, C R, O'Hare, P
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Publishing Group 1989
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401167/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2676518/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08361.x
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