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Human Immunodeficiency Virus Type 1 Central DNA Flap: Dynamic Terminal Product of Plus-Strand Displacement DNA Synthesis Catalyzed by Reverse Transcriptase Assisted by Nucleocapsid Protein

To terminate the reverse transcription of the human immunodeficiency virus type 1 (HIV-1) genome, a final step occurs within the center of the proviral DNA generating a 99-nucleotide DNA flap (6). This step, catalyzed by reverse transcriptase (RT), is defined as a discrete strand displacement (SD) s...

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Publicado no:J Virol
Principais autores: Hameau, Laurence, Jeusset, Josette, Lafosse, Sophie, Coulaud, Dominique, Delain, Etienne, Unge, Torsten, Restle, Tobias, Le Cam, Eric, Mirambeau, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114123/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.7.3301-3313.2001
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